No, I've only run it on Mono built from svn, haven't tested with release versions of Mono but I suspect it works fairly well with the latest release. It runs pretty well but still has some issues. I've noticed that AggregateCacheDependency doesn't seem to work well with an inner FileDependency. It doesn't seem to notice when the file is modified. This can be worked around by disabling cache in mojoPortal but it needs to be reported as a bug.

Anyone who would like to help testing please do. Anything we can report to the Mono team they seem to fix quickly. I've just been busy with project work and haven't had as much time as I would like to test everything thoroughly myself.

If you have the latest release of Mono and MonoDevelop you can checkout mojoPortal from svn/branches/2.x and help testing. Helpful info:
http://www.mojoportal.com/gettingthecodewithsvn.aspx
http://www.mojoportal.com/workingwiththesourcecodeinmonodevelop.aspx
http://www.mojoportal.com/settingadatalayerreferenceinmonodevelop.aspx

You'll also need either PostgreSQL or MySql

Cheers,

Joe