I assure you that you can ignore that file, yes it got deployed in the package but the package is still the correct build for .NET 4.
Your first post said this:
Description: Request Validation has detected a potentially dangerous client input value, and processing of the request has been aborted. This value may indicate an attempt to compromise the security of your application, such as a cross-site scripting attack. To allow pages to override application request validation settings, set the requestValidationMode attribute in the httpRuntime configuration section to requestValidationMode="2.0".
and the mojoPortal package for .NET 4 does have this in Web.config so it would not throw that error:
<httpRuntime requestValidationMode="2.0" maxUrlLength="560" maxQueryStringLength="2048" />
therefore I conclude that you installed the 3.5 version of mojoPortal which does not have this.
Please try re-deploy the mojoPortal 2.3.5.5.mssql-net40-deploymentfiles.zip
Hope it helps,
Joe