i really dont know much about this website builder but i get a error when i try to upload pictures to a website i created :(

Forgive me im a noob and i used the iis thing to set up my site on a windows server 2003  this s the error i got

[DirectoryNotFoundException: Could not find a part of the path.]
   System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath) +7712021
   System.IO.__Error.WinIOError() +33
   System.IO.FileInfo.MoveTo(String destFileName) +214
   Brettle.Web.NeatUpload.FilesystemUploadedFile.MoveTo(String path, MoveToOptions opts) +124
   Brettle.Web.NeatUpload.InputFile.MoveTo(String path, MoveToOptions opts) +51
   mojoPortal.Web.GalleryUI.GalleryImageEdit.btnUpdate_Click(Object sender, EventArgs e) +1045
   System.Web.UI.WebControls.Button.OnClick(EventArgs e) +111
   System.Web.UI.WebControls.Button.RaisePostBackEvent(String eventArgument) +110
   System.Web.UI.WebControls.Button.System.Web.UI.IPostBackEventHandler.RaisePostBackEvent(String eventArgument) +10
   System.Web.UI.Page.RaisePostBackEvent(IPostBackEventHandler sourceControl, String eventArgument) +13
   System.Web.UI.Page.RaisePostBackEvent(NameValueCollection postData) +36
   System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint) +1565

anyone have any ideas?