Mats, when we bought Artisteer, we went for the Standard version. Of course we didn't need that for the other CMS output formats, but you do get a lot more graphics, textures, fonts, and color schemes in Standard. The difference in price was already more than made up in time savings on my first developed skin!
As for the options dialog, I believe with the Home version you can still select from "generic" width options, but with the options dialog you can fine tune the settings. For my first skin I went with standard page (1000 px) and column (medium) widths, and it works great. I may fine tune the side columns to make them a little narrower though, and that's something you probably couldn't do with the Home version ("small" is too small, and "medium" is a little bigger than it needs to be, IMO). I'm also slightly concerned that 1000 px wide will cause a horizontal scroll bar on a 1024x768 display. I think the safest maximum for that is around 960, but I need to test it. Again, that would only be possible with Standard, I believe.
Also, don't forget to use the mojoPortal.com click-through affiliate link when you're ready to buy. We need to keep Joe happily working on mojoPortal for many years to come. 