Hi Finn,
This is an upgrade right? Not a new installation. A new installation should start at 2.2.4.8 script.
If this is an upgrade what I would do is try copying the script ~/Setup/applications/mojopprtal-core/SchemaUpgradeScripts/mssql/2.2.1.9.config into query analyzer and run it from there. You will see parts of the script are renaming some columns. If those are the parts casuing the error then just manually change the column nnames and drop those parts out of the script. f you get through that script in Query Analyzer, then update the version in MP_SchemaVersion to 2.2.1.9, then you can revisit the setup page and maybe none of the other scripts will have problems.
Sorry for the difficulty, that script did work for me in testing.
If this is a SQL server you have control over, I would make sure its up to date on all service packs.
Best,
Joe