Hi,
If you are a developer then you should understand that web site software such as mojoPortal is just delivering html, css and javascript to the web browser and all rendering happens in the web browser.
Therefore if something is not rendering correctly the logical way to troubleshoot the problem is to find out if the css is being delivered or not. To do that you view the source of the rendered html and you follow the link to the css (ie csshandler.ashx?...)
Do you see CSS or do you see an error?
If you see an error find out what it is and solve it. The most likely problem is if .ashx extension is not configured correctly to be handled by ASP.NET. If you have a lot of other stuff installed it can be a factor, there is a known problem when Cold Fusion is installed it can break some of the handler mappings for ASP.NET.
Hope that helps,
Joe
ps, in case you did not know, typing in all capital letters is considered the internet equivalent to shouting. Best not to shout when you are asking for help.